Understanding ADHD the hormonal neuroscience connection if your ADHD feels worse at certain times of the month or life. It’s not in your head. It’s hormonal neuroscience. ADHD isn’t a dopamine condition. It’s a dopamine and hormone interaction disorder. Here’s a science most people are never told estrogen directly supports, dopamine production and transport. Dopamine is the chemical ADHD brains already struggled to regulate when estrogen is stable or high ADHD symptoms often feel more manageable