Europe PMC

Chemicals seeping from the sea floor sustain an extreme-depth ecosystem.

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Europe PMC

Female Sexual Function and Pelvic Floor Muscle Training: A Narrative Review

Europe PMC is an archive of life sciences journal literature.
Europe PMC

Effect of early initiation of noninvasive ventilation in patients transported by emergency medical service for acute heart failure.

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Europe PMC

Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.

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Europe PMC

The Endeavor to Predict Depression and Anxiety Trajectories in the Context of Chronic Diseases Remains a Formidable Challenge.

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Europe PMC

Glycolytic enzymes in non-glycolytic web: functional analysis of the key players.

To survive in the tumour microenvironment, cancer cells undergo rapid metabolic reprograming and adaptability. One of the key characteristics of cancer is increased glycolytic selectivity and ...
Europe PMC

Where developmental toxicity meets explainable artificial intelligence: state-of-the-art and perspectives.

The application of Artificial Intelligence (AI) to predictive toxicology is rapidly increasing, particularly aiming to develop non-testing methods that effectively address ethical concerns and reduce ...
Europe PMC

Who Should-and Can-Get Lecanemab, the New Alzheimer Disease Drug?

Europe PMC is an archive of life sciences journal literature.
Europe PMC

High-resolution structural-omics of human liver enzymes.

We applied raw human liver microsome lysate to a holey carbon grid and used cryo-electron microscopy (cryo-EM) to define its composition. From this sample we identified and simultaneously determined ...
Europe PMC

The evolution of motivational interviewing.

This review traces the development of motivational interviewing (MI) from its happenstance beginnings and the first description published in this journal in 1983, to its continuing evolution as a ...
Europe PMC

Predicting Protein-Peptide Interactions: Benchmarking Deep Learning Techniques and a Comparison with Focused Docking.

The accurate prediction of protein structures achieved by deep learning (DL) methods is a significant milestone and has deeply impacted structural biology. Shortly after its release, AlphaFold2 has ...
Europe PMC

Direct Use of Clinical Tolerance Limits for Assessing the Degree of Agreement between Two Methods of Measuring Blood Pressure.

A large number of new methods of measuring blood pressure (BP) have recently emerged with advances in technology. Different methods of measuring BP generally provide varying readings compared with one ...