Organs often have fluid-filled spaces called lumens, which are crucial for organ function and serve as transport and delivery ...

A large team of researchers led by Wouter Karthaus, head of the Endocrine Therapy Resistance and Molecular Genetics Lab at ...

Transverse tubules (T-tubules) play a significant role in muscle contraction. However, the underlying mechanism of their ...

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery ...

Recently, a novel procedure, ORF (an acronym for ostensible recognition of folds), was developed to identify protein homologs in genomic databases 1. As an initial test, ORF was used to predict a gene ...

A new study reveals that roasted coffee contains previously unknown compounds capable of inhibiting a key enzyme linked to blood sugar control. Scientists have identified three compounds that strongly ...

Enzymes have long captivated biologists and chemists by performing difficult reactions rapidly and selectively in aqueous environments. The designs of enzymes catalyzing a retro-aldol reaction and a ...

AlphaFold arrived as a technical moonshot that suddenly made protein structures feel like software rather than secrets of nature, and five years on it has rewired how laboratories plan experiments, ...

AI’s growing influence in pharma is transforming traditional drug discovery timelines. In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Dr Alan Roth, CEO of Oxford Drug Design, ...

Rutger Bregman's 2025 Reith Lectures, called "Moral Revolution", explore the moral decay and un-seriousness of today's elites, drawing historical parallels to past eras of corruption that preceded ...

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