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How chromosomes shape up for cell division: Scientists reveal DNA loop formation mechanisms
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...
Scientists at the Stowers Institute for Medical Research have, for the first time, identified the exact location where human chromosomes break and fuse to form Robertsonian chromosomes. The discovery ...
Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...
The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...
Robertsonian chromosomes are large chromosomes that form when the long arm of a chromosome breaks and fuses with another chromosome. They are the most common type of chromosome rearrangement in humans ...
A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. A research group has demonstrated that overexpression of ...
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