A vaccine in development would be the first proactive treatment for overdose and fentanyl addiction, if approved. A vaccine ...

USC Dornsife College of Letters, Arts and Sciences and University of Southern California provide funding as members of The Conversation US. Naloxone, also known by the brand name Narcan, is one of the ...

Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States' fight against the opioid crisis. It reverses an opioid overdose nearly instantly, restarting ...

Dornsife researchers created 3D models of opioids hitting brain receptors, and of naloxone stopping the receptors from activating. (Henry Kofman / Daily Trojan file photo) The opioid crisis has killed ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Chronic pain is one of the most common and expensive health problems in the nation, affecting an estimated one in five U.S. adults and costing around $600 billion each year in medical expenses, lost ...

Ketamine use disorder is a serious and growing problem of increased non-prescribed ketamine use among young users, ages 16-30. Linda Cottler, Ph.D., and her fellow researchers at the University of ...

One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the 19th century. Morphine molecules act as painkillers by attaching themselves to ...

Duke University researchers have devised a promising, potent pain reliever — seemingly without the harmful side effects and addictive highs of opioids. While opioids interact with numerous cellular ...

C. Michael White does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...