Cells use Morse code-like rhythms to coordinate growth

Cells experience many different types of stress, such as starvation or stress caused by too much salt or too high a temperature. Insulin signals respond to such stress signals by sending the protein ...
中国日报网

Scientists break ground on DNA synthesis

Industrial biotechnology researchers work in a laboratory affiliated with the Chinese Academy of Sciences in Tianjin in January last year. [Photo/Xinhua] A recent breakthrough in synthetic biology in ...
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
Research Matters

Beyond the Double Helix: How four-stranded DNA ‘knots’ helps proteins fold

Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...
How-To Geek on MSN

How to use the SCAN function in Microsoft Excel to calculate running totals

The SCAN function lives in a single cell and spills the results down the column, ensuring my totals are always structurally ...
Hosted on MSN

6 Functions That Changed How You Use Microsoft Excel

The introduction of dynamic arrays triggered the biggest change to how we work with Microsoft Excel formulas in years, if not decades. They allow a single formula to spill multiple results into ...
eLife

Importance of higher-order epistasis in protein sequence-function relationships

In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...
The New York Times

Everyone Is Using A.I. for Everything. Is That Bad?

Either way, let’s not be in denial about it. Credit...Illustration by Christoph Niemann Supported by By Kevin Roose and Casey Newton Kevin Roose and Casey Newton are the hosts of The Times’s “Hard ...
EurekAlert!

Expanding the sequence spaces of synthetic binding protein using deep learning-based framework ProteinMPNN

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...
Geeky Gadgets

3 Simple Excel Tricks to Save Hours of Work

Have you ever spent hours manually updating a spreadsheet, only to realize there’s a faster, smarter way to get the job done? Excel is a tool most of us use, but few truly master. The irony? Some of ...
IEEE

Deep Learning-based Functional Prediction Model for Genome Sequence

Abstract: This study proposes a deep learning-based genome sequence function prediction model and systematically evaluates its performance. The study begins with an overview of the importance of ...