The tendency of actin to polymerize initially thwarted crystal production. Holmes and colleagues overcame this by complexing rabbit skeletal actin with DNase I, thereby preventing polymerization and ...

This is a preview. Log in through your library . Abstract Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive cellular processes such as lamellipodial protrusion and ...

A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists have now taken a ...

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...

Many actin binding proteins have a modular architecture, and calponin-homology (CH) domains are one such structurally conserved module found in numerous proteins that interact with F-actin. The manner ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

Researchers at Dresden University of Technology reveal that early zebrafish embryos divide without a closed actin ring.

The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...