There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University’s College of Medicine and the UMass Chan Medical School have achieved ...

Hereditary Spastic Paraplegia (HSP) encompasses a heterogeneous group of genetic neurodegenerative disorders primarily characterised by progressive lower-limb spasticity and weakness. The condition ...

In a recent publication in Molecular Therapy, researchers from Drexel University College of Medicine and UMass Chan Medical School presented a silence-and-replace gene therapy strategy aiming to ...

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Boston Children’s Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., ...