Strike while the iron is hot, advises the old adage. Chemists in California have now taken that blacksmith’s advice to heart, using an iron catalyst to forge secondary amines from nitroarenes and ...
A University of Illinois at Urbana-Champaign research team has discovered a way to produce a special class of molecule that could open the door for new drugs to treat currently untreatable diseases.
A research team has discovered a new chemical reaction that provides a simple, rapid way of making tertiary amines -- swinging the door wide open to the discovery of new medicinal compounds. A ...
New research presents a versatile method for the synthesis of primary, secondary, and tertiary amines containing two stereogenic centers. In a paper just published at the website of ACS Catalysis, the ...
Amines are an important class of organic compounds. Students might be aware that adrenaline and ephedrine, which contain secondary amino groups, are used to increase blood pressure. Novocain which is ...
In a showcase of metal hydride catalysis, two research groups have developed reactions to transform simple unsaturated building blocks—alkenes and alkynes—into valuable chiral amine products. What ...
This article presents an overview of FDA’s recent update to the guidance document, Control of Nitrosamine Impurities in Human Drugs. In September 2024, the much-anticipated update to FDA’s Guidance ...
Although enamine and SOMO catalysis represent powerful approaches to α-functionalization of aldehydes (Fig. 1a,c), to our knowledge, methods for direct β-functionalization of simple aldehydes rather ...
Nitrosamine impurities became a topic of focus when health regulators recalled valsartan, an antihypertensive drug, due to the presence of N-nitrosodimethylamine (NDMA), a probable carcinogenic agent ...
Formosa Petrochemical Corp. (FPCC) reduced the mass flow rate to regeneration and increased the absorption and regeneration capacity at its amine treating regeneration system after replacing ...
In a paper just published at the website of ACS Catalysis, the Biocatalysis research group at the University of Amsterdam’s Van ‘t Hoff Institute for Molecular Synthesis presents a versatile method ...
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