A 7-year-old boy was brought to a hospital with a 3-month history of cognitive deterioration and seizures. He had contracted measles at 7 months of age while living in an area where the ...

This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

A survey of the NEJM Catalyst Insights Council finds that health care leaders are exploring many uses of artificial ...

The March 2026 issue of NEJM Catalyst Innovations in Care Delivery is a special theme issue on the hard work of implementing artificial intelligence in real-world ...

When a physician’s own incidental finding sends her down a long and winding path to find answers, she finds herself overcome with worry — but also, eventually, a new appreciation for life.

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 22).

Early approaches to restricting abortion access, directed mainly at patients (the demand side of the market), had relatively little impact on national abortion rates. So abortion opponents have turned ...

Exercise rehabilitation has a long history in the management of chronic heart failure, with the first randomized trial of exercise training dating back to 1990 1 — and by the late 1990s, it had become ...

An organization that provides community-based care management services for Medicaid patients has developed, deployed, and iteratively enhanced an artificial ...

This work explores the perspectives of surgical patients with limited English proficiency on two modes of interpretation, artificial intelligence–based and remote ...

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 21).