What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

Top: Random Illumination Microscopy (RIM) utilizes random speckle patterns to achieve super-resolution imaging of biological tissues, improving resolution by a factor of two compared to the optical ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of ...

In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of Biophysics of the Chinese Academy of Sciences has developed a ...

SIMIP enables high-resolution images rich in both chemical and spatial information. A quantum cascade laser (QCL) excites molecular vibrations while a spatial light modulator (SLM) generates striped ...

Scientists have made a groundbreaking discovery in the field of nanotechnology. They have developed a novel microscopy method that allows for the unprecedented visualization of nanostructures and ...

Image by the US National Institutes of Health, CC 3.0 Image by the US National Institutes of Health, CC 3.0 A new dual-light microscope lets researchers observe micro- and nanoscale activity inside ...

This is especially true when studying intricate details beyond the optical resolution limit using structured illumination microscopy (SIM). SIM uses multiple images acquired under structured ...

Peking University, Aug 18, 2025: Professor Xi Peng’s team from the College of Future Technology at Peking University has recently developed a triangle structured illumination microscopy (SIM), which ...