The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular ...

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

Life begins with a quiet but precise choreography inside the nucleus. For decades, scientists believed that a newly fertilized egg started in disorder, its DNA loosely arranged and waiting for ...

Around 8 percent of human DNA is made up of genetic sequences acquired from ancient viruses. These sequences, known as human endogenous retroviruses (or Hervs), date back hundreds of thousands to ...

Researchers have identified a specific class of brain neurons that dies during multiple sclerosis because inflammation ...